Structure of PDB 3qx7 Chain A

Receptor sequence
>3qx7A (length=224) Species: 818 (Bacteroides thetaiotaomicron) [Search protein sequence]
HMRKKLKAVLFDMDGVLFNSMPYHSEAWHQVMKTHGLDLSREEAYMHEGR
TGASTINIVFQRELGKEATQEEIESIYHEKSILFNSYPEAERMPGAWELL
QKVKSEGLTPMVVTGSGQLSLLERLEHNFPGMFHKELMVTAFDVKYGKPN
PEPYLMALKKGGLKADEAVVIENAPLGVEAGHKAGIFTIAVNTGPLDGQV
LLDAGADLLFPSMQTLCDSWDTIM
3D structure
PDB3qx7 Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D11 D13 S19 E47 V112 T113 K147 E171 N172
Catalytic site (residue number reindexed from 1) D12 D14 S20 E48 V113 T114 K148 E172 N173
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A Y76 K79 G116 Q117 Y77 K80 G117 Q118
BS02 PO4 A H28 K32 R40 H29 K33 R41
BS03 MG A D11 D13 E47 N172 D12 D14 E48 N173
Gene Ontology
Molecular Function
GO:0008801 beta-phosphoglucomutase activity
GO:0046872 metal ion binding
GO:0050308 sugar-phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:3qx7, PDBe:3qx7, PDBj:3qx7
PDBsum3qx7
PubMed21894910
UniProtQ8A5V9

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