Structure of PDB 3qvf Chain A

Receptor sequence
>3qvfA (length=274) Species: 43759 (Streptomyces wedmorensis) [Search protein sequence]
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFAR
LAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAE
KLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALF
DEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDGAGGDTILPE
VDARSPEQAYAALWGSSEWDATGAMHTKLDALVTCARRGAECFIMRGDPG
SDLEFLTAPFSSWPAHVRSTRITT
3D structure
PDB3qvf Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.26: isopentenyl phosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G11 S13 K18 T170 D171 V172 I175 V176 A200 L201 W202 M213 K216 G23 S25 K30 T182 D183 V184 I187 V188 A212 L213 W214 M225 K228
BS02 FV1 A K9 G12 K18 G52 G53 G54 H58 S148 S149 T210 K21 G24 K30 G64 G65 G66 H70 S160 S161 T222
Gene Ontology
Molecular Function
GO:0004349 glutamate 5-kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0102043 isopentenyl phosphate kinase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3qvf, PDBe:3qvf, PDBj:3qvf
PDBsum3qvf
PubMed21728358
UniProtQ56187

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