Structure of PDB 3quy Chain A

Receptor sequence
>3quyA (length=268) Species: 10090 (Mus musculus) [Search protein sequence]
KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQ
GKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCE
MYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQG
TSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVS
GFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGL
ACRVKHSSLGGQDIILYW
3D structure
PDB3quy Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUC A S114 G130 N165 S109 G125 N160
BS02 QUY A S28 L66 H68 M69 Y73 S76 D80 L100 W133 D153 G155 T156 T159 F171 S23 L61 H63 M64 Y68 S71 D75 L95 W128 D148 G150 T151 T154 F166 MOAD: Kd=187nM
External links
PDB RCSB:3quy, PDBe:3quy, PDBj:3quy
PDBsum3quy
PubMed21552205
UniProtP11609|CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 (Gene Name=Cd1d1)

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