Structure of PDB 3quo Chain A

Receptor sequence
>3quoA (length=265) Species: 43759 (Streptomyces wedmorensis) [Search protein sequence]
HHSSGLVPRGSHMTPDFLAIKVGGSLFSRKDEPGSLDDDAVTRFARNFAR
LAETYRGRMVLISGGGAFGHGAIRDHDSTHAFSLAGLTEATFEVKKRWAE
KLRGIGVDAFPLQLAAMCTLRNGIPQLRSEVLRDVLDHGALPVLAGDALF
DEHGKLWAFSSDRVPEVLLPMVEGRLRVVTLTDVDGIVTDTILPEVDARS
PEQAYAALWGSSAMHTKLDALVTCARRGAECFIMRGDPGSDLEFLTAPFS
SWPAHVRSTRITTTA
3D structure
PDB3quo Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.26: isopentenyl phosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G11 G12 S13 K18 T170 D171 V172 G174 I175 V176 A200 L201 S204 S205 A212 M213 K216 G23 G24 S25 K30 T182 D183 V184 G186 I187 V188 A207 L208 S211 S212 A213 M214 K217
BS02 FCN A G52 G53 S148 S149 G64 G65 S160 S161
Gene Ontology
Molecular Function
GO:0004349 glutamate 5-kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0102043 isopentenyl phosphate kinase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0008299 isoprenoid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3quo, PDBe:3quo, PDBj:3quo
PDBsum3quo
PubMed21728358
UniProtQ56187

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