Structure of PDB 3qo8 Chain A

Receptor sequence
>3qo8A (length=441) Species: 5476 (Candida albicans) [Search protein sequence]
MLDINAFLVEKGGDPEIIKASQKKRGDSVELVDEIIAEYKEWVKLRFDLD
EHNKKLNSVQKEIGKRFKDAKDLIAEKEKLSNEKKEIIEKEAEADKNLRS
KINQVGNIVHESVVDSQDEENNELVRTWTPENYKKPEQIAAATGAPAKLS
HHEVLLRLDGYDPERGVRIVGHRGYFLRNYGVFLNQALINYGLSFLSSKG
YVPLQAPVMMNKEVMAKTAQLSQFDEELYKVIDGEDEKYLIATSEQPISA
YHAGEWFESPAEQLPVRYAGYSSCFRREAGSHGKDAWGIFRVHAFEKIEQ
FVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGELNNAAAKKYD
LEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCGIKKYVHCLNSTLSATER
TICCILENYQKEDGLVIPEVLRKYIPGEPEFIPYIKELPKN
3D structure
PDB3qo8 Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R279 R294 E366 S369 R410
Catalytic site (residue number reindexed from 1) R276 R291 E363 S366 R400
Enzyme Commision number 6.1.1.11: serine--tRNA ligase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004828 serine-tRNA ligase activity
GO:0005524 ATP binding
GO:0140101 catalytic activity, acting on a tRNA
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006434 seryl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3qo8, PDBe:3qo8, PDBj:3qo8
PDBsum3qo8
PubMed21825144
UniProtQ9HGT6|SYSC_CANAL Serine--tRNA ligase, cytoplasmic (Gene Name=SES1)

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