Structure of PDB 3qmh Chain A

Receptor sequence
>3qmhA (length=53) Species: 9606 (Homo sapiens) [Search protein sequence]
ARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARES
YKY
3D structure
PDB3qmh The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R167 R200 Q201 K202 R213 R2 R35 Q36 K37 R48 PDBbind-CN: Kd=17uM
BS02 dna A I199 R200 Q201 S215 I34 R35 Q36 S50 PDBbind-CN: Kd=17uM
BS03 ZN A C169 C172 C175 C208 C4 C7 C10 C43
BS04 ZN A C181 C184 C187 C203 C16 C19 C22 C38
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:3qmh, PDBe:3qmh, PDBj:3qmh
PDBsum3qmh
PubMed21407193
UniProtQ9P0U4|CXXC1_HUMAN CXXC-type zinc finger protein 1 (Gene Name=CXXC1)

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