Structure of PDB 3qmb Chain A

Receptor sequence
>3qmbA (length=54) Species: 9606 (Homo sapiens) [Search protein sequence]
RSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRAR
ESYK
3D structure
PDB3qmb The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
ChainA
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K202 I203 R204 K35 I36 R37 PDBbind-CN: Kd=3.5uM
BS02 dna A R171 R204 Q205 K206 R210 R217 R4 R37 Q38 K39 R43 R50 PDBbind-CN: Kd=3.5uM
BS03 ZN A C173 C176 C179 C212 C6 C9 C12 C45
BS04 ZN A C185 C188 C191 C207 C18 C21 C24 C40
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:3qmb, PDBe:3qmb, PDBj:3qmb
PDBsum3qmb
PubMed21407193
UniProtQ9P0U4|CXXC1_HUMAN CXXC-type zinc finger protein 1 (Gene Name=CXXC1)

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