Structure of PDB 3qm0 Chain A

Receptor sequence
>3qm0A (length=355) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SMSLNDFLSSVLPVSEQFEYLSLQSIPLETHAVVTPNKDDKRVPKSTIKT
QHFFSLFHQGKVFFSLEVYVYVTLWDEADAERLIFVSKADTNGYCNTRVS
VRDITKIILEFILSIDPNYYLQKVKPAIRSTCPREILTKICLFTRPASQY
LFPDSSKNSKKHILNGEELMKWWGFILDRLLIECFQNDTQAKLRIPGEDP
ARVRSYLRGMKYPLWQVGDIFTSKENSLAVYNIPLFPDDPKARFIHQLAE
EDRLLKVSLSSFWIELQERQEFKLSVTSSVMGISGYSLATPSLFPSSADV
IVPKSRKQFRAIKKYITGEEYDTEEGAIEAFTNIRDFLLLRMATNLQSLT
GKREH
3D structure
PDB3qm0 Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO A A88 D89 T90 R97 V100 R101 F192 A196 Y199 H211 I212 L213 L218 W222 A89 D90 T91 R98 V101 R102 F143 A147 Y150 H162 I163 L164 L169 W173
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0010484 histone H3 acetyltransferase activity
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3qm0, PDBe:3qm0, PDBj:3qm0
PDBsum3qm0
PubMed18568037
UniProtQ07794|RT109_YEAST Histone acetyltransferase RTT109 (Gene Name=RTT109)

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