Structure of PDB 3ql9 Chain A

Receptor sequence
>3ql9A (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
SMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSD
GMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDENNQWY
CYICHPEPLLDLVTACNSVYENLEQ
3D structure
PDB3ql9 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
ChainA
Resolution0.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y203 D207 M216 D217 E218 Q219 A224 E225 G226 G227 N228 L229 I230 C231 M257 Y39 D43 M52 D53 E54 Q55 A60 E61 G62 G63 N64 L65 I66 C67 M93
BS02 ZN A C171 C174 C197 C200 C7 C10 C33 C36
BS03 ZN A C220 C223 C240 C243 C56 C59 C76 C79
BS04 ZN A C232 C235 C265 C268 C68 C71 C101 C104
External links
PDB RCSB:3ql9, PDBe:3ql9, PDBj:3ql9
PDBsum3ql9
PubMed21666679
UniProtP46100|ATRX_HUMAN Transcriptional regulator ATRX (Gene Name=ATRX)

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