Structure of PDB 3qku Chain A

Receptor sequence
>3qkuA (length=359) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLLDAILVGLYWP
LRIKDIKKDEFTKVGARDTYIDLIFEKDGTKYRITRRFLKGYSSGEIHAM
KRLVGNEWKHVTEPSSKAISAFMEKLIPYNIFLNAIYIRQGQIDAILESD
EAREKVVREVLNLDKFETAYKKLSELKKTINNRIKEYGGSGGIKDLEKAK
DFTEELIEKVKKYKALAREAALSKIGELASEIFAEFTEGKYSEVVVRAEE
NKVRLFVVWEGKERPLTFLSGGERIALGLAFRLAMSLYLAGEISLLILDE
PTPYLDEERRRKLITIMERYLKKIPQVILVSHDEELKDAADHVIRISLEN
GSSKVEVVS
3D structure
PDB3qku ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
ChainA
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A R12 S13 N32 G33 S34 G35 K36 S37 S38 K63 V64 Q140 R12 S13 N32 G33 S34 G35 K36 S37 S38 K63 V64 Q140
BS02 MG A S37 Q140 S37 Q140
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3qku, PDBe:3qku, PDBj:3qku
PDBsum3qku
PubMed21441914
UniProtP58301|RAD50_PYRFU DNA double-strand break repair Rad50 ATPase (Gene Name=rad50)

[Back to BioLiP]