Structure of PDB 3qem Chain A

Receptor sequence
>3qemA (length=355) Species: 8355 (Xenopus laevis) [Search protein sequence]
DPKIVNIGAVLSTKKHEQIFREAVNQANKRHFTRKIQLQATSVTHRPNAI
QMALSVCEDLISSQVYAILVSHPPLTPTPISYTAGFYRIPVIGLTTRMSI
YSDKSIHLSFLRTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQ
KKLETLLEGPKADKVLQFEPGTKNLTALLLEAKELEARVIILSASEDDAT
AVYKSAAMLDMTGAGYVWLVGEREISGSALRYAPDGIIGLQLINGKNESA
HISDAVAVVAQAIHELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSK
YPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFNGSYIIQNDRKI
IWPGG
3D structure
PDB3qem Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
ChainA
Resolution3.003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 QEM A Y109 T110 R115 S132 L135 Y82 T83 R88 S105 L108 PDBbind-CN: -logKd/Ki=7.22,Kd=60nM
External links
PDB RCSB:3qem, PDBe:3qem, PDBj:3qem
PDBsum3qem
PubMed21677647
UniProtA0A1L8F5J9|NMDZ1_XENLA Glutamate receptor ionotropic, NMDA 1 (Gene Name=grin1)

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