Structure of PDB 3q7i Chain A

Receptor sequence
>3q7iA (length=541) Species: 177416 (Francisella tularensis subsp. tularensis SCHU S4) [Search protein sequence]
NAMLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLI
NDYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTP
LIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGS
DLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLLIIAS
KSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDL
EHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKET
EFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESN
GKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIA
TSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKEL
AAHKVIPGNRPSTTILLDELSPYSLGALIALYEHKIFVQGVLWDINSYDQ
WGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKN
3D structure
PDB3q7i Glucose-6-phosphate isomerase from Francisella tularensis.
ChainA
Resolution1.54 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K199 E205 G260 R261 E346 H377 K505
Catalytic site (residue number reindexed from 1) K201 E207 G262 R263 E348 H379 K507
Enzyme Commision number 5.3.1.9: glucose-6-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6PG A I145 G147 S198 K199 S200 T203 G260 R261 Q342 E346 K505 I147 G149 S200 K201 S202 T205 G262 R263 Q344 E348 K507
Gene Ontology
Molecular Function
GO:0004347 glucose-6-phosphate isomerase activity
GO:0016853 isomerase activity
GO:0048029 monosaccharide binding
GO:0097367 carbohydrate derivative binding
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
GO:0051156 glucose 6-phosphate metabolic process
GO:1901135 carbohydrate derivative metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3q7i, PDBe:3q7i, PDBj:3q7i
PDBsum3q7i
PubMed
UniProtQ5NFC4|G6PI_FRATT Glucose-6-phosphate isomerase (Gene Name=pgi)

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