Structure of PDB 3q60 Chain A

Receptor sequence
>3q60A (length=350) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
AGDSFMRDLLKREEELIGYCREEALKEPAAMVEAVTATVWPQNAETTVDS
LLSQGERKLKLVEPLRVGDRSVVFLVRDVERLEDFALKVFTMGAENSRSE
LERLHEATFAAARLLGRLLLPSDAVAVQSQPPFAQLSPGYAVANYLLLMP
AASVDLELLFSTLDFVYVFRGDEGILALHILTAQLIRLAANLQSKGLVHG
HFTPDNLFIMPDGRLMLGDVSALWKVGTRGPASSVPVTYAPREFLNASTA
TFTHALNAWQLGLSIYRVWCLFLPFGLVTPGIKGSWKRPSLRVPGTDSLA
FGSCTPLPDFVKTLIGRFLNFDRRRRLLPLEAMETPEFLQLQNEISSSLS
3D structure
PDB3q60 A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
ChainA
Resolution1.72 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A R241 G243 D244 R245 S246 A261 K263 M337 A340 D343 D393 F396 R66 G68 D69 R70 S71 A86 K88 M149 A152 D155 D205 F208
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3q60, PDBe:3q60, PDBj:3q60
PDBsum3q60
PubMed21708941
UniProtF2YGR7

[Back to BioLiP]