Structure of PDB 3q5i Chain A

Receptor sequence

>3q5iA (length=470) Species: 5821 (Plasmodium berghei) [Search protein sequence]

GRENLYFQGIAINPGMYVRKKEGKIGESYFKVRKLGSYGEVLLCKEKNGH
SEKAIKVIKKKFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEF
YEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVHRDIKPENI
LLENKNSLLNIKIVDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNEK
CDVWSCGVIMYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISDE
AKELIKLMLTYDYNKRCTAEEALNSRWIKKYANNINKSDQKTLCGALSNM
RKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKEL
IEGYNVLRNFKLGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQ
ILFSEERLRRAFNLFDTDKSGKITKEELANLFGLTSISEKTWNDVLGEAD
QNKDNMIDFDEFVSMMHKIC

3D structure

PDB

3q5i Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420

Chain

Resolution

2.1 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	A	D384 N386 D388 Q390 E395	D338 N340 D342 Q344 E349
BS02	CA	A	E31 Y34 F35 Q36	E3 Y6 F7 Q8
BS03	CA	A	D428 D430 N432 Y434 E436 E439	D380 D382 N384 Y386 E388 E391
BS04	CA	A	D464 D466 S468 K470 E475	D416 D418 S420 K422 E427
BS05	CA	A	D498 N500 D502 M504 E509	D450 N452 D454 M456 E461
BS06	CA	A	N195 D211	N149 D165
BS07	ANP	A	V71 A84 K86 F146 Y147 E151 L197 D211	V41 A54 K56 F100 Y101 E105 L151 D165

Gene Ontology

	Molecular Function
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004683	calcium/calmodulin-dependent protein kinase activity
GO:0005509	calcium ion binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0009931	calcium-dependent protein serine/threonine kinase activity
GO:0044024	histone H2AS1 kinase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006338	chromatin remodeling
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0035556	intracellular signal transduction
GO:0045727	positive regulation of translation
GO:0046777	protein autophosphorylation
GO:2000147	positive regulation of cell motility

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0020002	host cell plasma membrane
GO:0020005	symbiont-containing vacuole membrane
GO:0031514	motile cilium

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:3q5i, PDBe:3q5i, PDBj:3q5i
PDBsum	3q5i
PubMed
UniProt	A0A509AHB6\|CDPK1_PLABA Calcium-dependent protein kinase 1 (Gene Name=CDPK1)

[Back to BioLiP]