Structure of PDB 3q5e Chain A

Receptor sequence
>3q5eA (length=411) Species: 9606 (Homo sapiens) [Search protein sequence]
KKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKG
KSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEI
FLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLS
QNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGA
DGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATN
PNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYF
KAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDK
PFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELY
IQYIKHNDSKN
3D structure
PDB3q5e Structural basis for the nucleotide-dependent dimerization of the large G protein atlastin-1/SPG3A.
ChainA
Resolution3.013 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A R77 G79 K80 S81 F82 R217 D218 P272 V276 N279 R48 G50 K51 S52 F53 R188 D189 P243 V247 N250
BS02 MG A K80 S81 D146 Q148 K51 S52 D117 Q119
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3q5e, PDBe:3q5e, PDBj:3q5e
PDBsum3q5e
PubMed21220294
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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