Structure of PDB 3q4k Chain A

Receptor sequence
>3q4kA (length=356) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MKFTVEREHLLKPLQQVSTLPILGNLLLQVADGTLSLTGTDLEMEMVARV
ALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFS
LSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNG
MLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRML
DGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPPDKHLEAG
CDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVT
YSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAY
VVMPMR
3D structure
PDB3q4k Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A T172 G174 H175 R176 P242 Y244 V247 M362 P363 M364 R365 T165 G167 H168 R169 P235 Y237 V240 M353 P354 M355 R356
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006974 DNA damage response
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0032297 negative regulation of DNA-templated DNA replication initiation
GO:0042276 error-prone translesion synthesis
GO:0044787 bacterial-type DNA replication
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009360 DNA polymerase III complex
GO:0030894 replisome
GO:1990078 replication inhibiting complex
GO:1990085 Hda-beta clamp complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3q4k, PDBe:3q4k, PDBj:3q4k
PDBsum3q4k
PubMed21619076
UniProtP0A988|DPO3B_ECOLI Beta sliding clamp (Gene Name=dnaN)

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