Structure of PDB 3q3c Chain A

Receptor sequence
>3q3cA (length=294) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
KQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSA
RDAVQGADVVISMLPASQHVEGLYLDDGLLAHIAPGTLVLECSTIAPTSA
RKIHAAARERGLAMLDAPVSGGTAGAAAGTLTFMVGGDAEALEKARPLFE
AMGRNIFHAGPDGAGQVAKVCNNQLLAVLMIGTAEAMALGVANGLEAKVL
AEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQLMAKDLGLAQ
EAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLFDPTQ
3D structure
PDB3q3c Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine Dehydrogenase.
ChainA
Resolution2.299 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.387: L-serine 3-dehydrogenase (NAD(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G10 H11 M12 F30 D31 L32 M64 L65 P66 T96 V121 G123 F239 K246 G9 H10 M11 F29 D30 L31 M63 L64 P65 T94 V119 G121 F237 K244
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006565 L-serine catabolic process
GO:0009083 branched-chain amino acid catabolic process
GO:0016054 organic acid catabolic process
GO:0051289 protein homotetramerization

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Molecular Function
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Biological Process
External links
PDB RCSB:3q3c, PDBe:3q3c, PDBj:3q3c
PDBsum3q3c
PubMed22128181
UniProtQ9I5I6|SERDH_PSEAE NAD-dependent L-serine dehydrogenase (Gene Name=PA0743)

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