Structure of PDB 3q1k Chain A

Receptor sequence
>3q1kA (length=357) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
AKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGIDKAGQWHV
NDAENYLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDV
IFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDA
GLNIAPFITLTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANE
AQYQQAVALAFEFDHKVVVEQGIKGREIECAVLGNDNPQASTCGEIVLNS
EFKYIDDNGAQVVVPAQIPSEVNDKIRAIAIQAYQTLGCAGMARVDVFLT
ADNEVVINEINTLPGFTNISMYPKLWQASGLGYTDLISRLIELALERHTA
NNALKTT
3D structure
PDB3q1k The Crystal Structure of the D-alanyl-alanine Synthetase A from Salmonella enterica Typhimurium Complexed with ADP
ChainA
Resolution2.202 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E16 V19 Q22 H107 S191 Y260 R300 D302 E315 N317 G321 I325
Catalytic site (residue number reindexed from 1) E15 V18 Q21 H106 S190 Y254 R294 D296 E309 N311 G315 I319
Enzyme Commision number 6.3.2.4: D-alanine--D-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A K141 F183 K185 S191 S192 E221 G223 I224 E228 F304 E315 K140 F182 K184 S190 S191 E220 G222 I223 E227 F298 E309
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0008716 D-alanine-D-alanine ligase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3q1k, PDBe:3q1k, PDBj:3q1k
PDBsum3q1k
PubMed
UniProtP0A1F0|DDLA_SALTY D-alanine--D-alanine ligase A (Gene Name=ddlA)

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