Structure of PDB 3q1i Chain A

Receptor sequence
>3q1iA (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
CHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKY
GLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNS
LMKKITLLKYFRNYMSEHLLKAGANITPRLPYLRTWFRTRSAIILHLSNG
SVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSSR
3D structure
PDB3q1i From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W414 D416 Y485 H489 L490 L491 R516 H538 K540 W43 D45 Y114 H118 L119 L120 R138 H160 K162
External links
PDB RCSB:3q1i, PDBe:3q1i, PDBj:3q1i
PDBsum3q1i
PubMed21472932
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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