Structure of PDB 3q0p Chain A

Receptor sequence
>3q0pA (length=341) Species: 9606 (Homo sapiens) [Search protein sequence]
GRSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAE
RQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLS
LALQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKC
IECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILE
ELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKF
ASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQK
MIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYY
3D structure
PDB3q0p Alternate modes of cognate RNA recognition by human PUMILIO proteins.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q860 R864 Q867 F897 N899 Y900 M932 Y933 R936 Q939 H972 R1008 Y1041 N1043 Y1044 K1076 F1077 N1080 E1083 Y1120 N1122 Y1123 Y1156 H1159 Q33 R37 Q40 F70 N72 Y73 M105 Y106 R109 Q112 H145 R181 Y214 N216 Y217 K249 F250 N253 E256 Y293 N295 Y296 Y329 H332 PDBbind-CN: Kd=0.4nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3q0p, PDBe:3q0p, PDBj:3q0p
PDBsum3q0p
PubMed21397187
UniProtQ14671|PUM1_HUMAN Pumilio homolog 1 (Gene Name=PUM1)

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