Structure of PDB 3pmv Chain A

Receptor sequence
>3pmvA (length=263) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFK
YKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVI
DFSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRS
KIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYI
EQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKL
KNKWWYDKGECGA
3D structure
PDB3pmv Structure based evolution of a novel series of positive modulators of the AMPA receptor.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A Y61 T91 R96 G141 S142 T143 E193 Y61 T91 R96 G141 S142 T143 E193
BS02 557 A I92 P105 F106 M107 S108 K218 G219 I92 P105 F106 M107 S108 K218 G219
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3pmv, PDBe:3pmv, PDBj:3pmv
PDBsum3pmv
PubMed21190850
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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