Structure of PDB 3pl3 Chain A

Receptor sequence

>3pl3A (length=436) Species: 68825 (Rasamsonia emersonii)

QQAGTATAENHPPLTWQECTAPGSCTTQNGAVVLDANWRWVHDVNGYTNC
YTGNTWDPTYCPDDETCAQNCALDGADYEGTYGVTSSGSSLKLNFVTGSN
VGSRLYLLQDDSTYQIFKLLNREFSFDVDVSNLPCGLNGALYFVAMDADG
GVSKYPNNKAGAKYGTGYCDSQCPRDLKFIDGEANVEGWQPSSNNANTGI
GDHGSCCAEMDVWEANSISNAVTPHPCDTPGQTMCSGDDCGGTYSNDRYA
GTCDPDGCDFNPYRMGNTSFYGPGKIIDTTKPFTVVTQFLTDDGTDTGTL
SEIKRFYIQNSNVIPQPNSDISGVTGNSITTEFCTAQKQAFGDTDDFSQH
GGLAKMGAAMQQGMVLVMSLWDDYAAQMLWLDSDYPTDADPTTPGIARGT
CPTDSGVPSDVESQSPNSYVTYSNIKFGPINSTFTA

3D structure

• PDB: 3pl3 ?
• Chain: A
• Resolution: 1.1804 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): E209 D211 E214 H225
• Catalytic site (residue number reindexed from 1): E209 D211 E214 H225
• Enzyme Commision number: 3.2.1.-
  3.2.1.91: cellulose 1,4-beta-cellobiosidase (non-reducing end).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BGC	A	R104 Y142 S369 W371	R104 Y142 S369 W371
BS02	BGC	A	W38 R104 D176	W38 R104 D176
BS03	BGC	A	N37 W38 V101	N37 W38 V101
BS04	BGC	A	W38 Y51 N100 K178	W38 Y51 N100 K178
BS05	BGC	A	W40 N49	W40 N49
BS06	BGC	A	D256 D343 R398	D256 D343 R398
BS07	BGC	A	R248 D256 W380	R248 D256 W380
BS08	BGC	A	Q172 W371 D373	Q172 W371 D373

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0016798 hydrolase activity, acting on glycosyl bonds

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0030245 cellulose catabolic process

External links

• PDB: RCSB:3pl3, PDBe:3pl3, PDBj:3pl3
• PDBsum: 3pl3
• UniProt: Q8TFL9