Structure of PDB 3pk0 Chain A

Receptor sequence
>3pk0A (length=260) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
GSMFDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRSTADIDACVA
DLDQLGSGKVIGVQTDVSDRAQCDALAGRAVEEFGGIDVVCANAGVFPDA
PLATMTPEQLNGIFAVNVNGTFYAVQACLDALIASGSGRVVLTSSITGPI
TGYPGWSHYGATKAAQLGFMRTAAIELAPHKITVNAIMPGNIMTEGLLEN
GEEYIASMARSIPAGALGTPEDIGHLAAFLATKEAGYITGQAIAVDGGQV
LPESLDAIAT
3D structure
PDB3pk0 Increasing the structural coverage of tuberculosis drug targets.
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G17 S143 W154 Y157 K161
Catalytic site (residue number reindexed from 1) G19 S145 W156 Y159 K163
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D51 G54 G56 D53 G56 G58
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3pk0, PDBe:3pk0, PDBj:3pk0
PDBsum3pk0
PubMed25613812
UniProtA0QQJ6

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