Structure of PDB 3pit Chain A

Receptor sequence
>3pitA (length=168) Species: 10090 (Mus musculus) [Search protein sequence]
LPTYKLVVVGDGGVGKSALTIQFFQKIFVPEYDPTIEDSYLKHTEIDNQW
AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLI
LRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDP
PLNVDKTFHDLVRVIRQQ
3D structure
PDB3pit Crystal structure of M-RasD41E in complex with GppNHp (type 2)
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G23 G25 K26 S27 A28 F38 V39 P40 E41 Y42 P44 T45 G70 N126 K127 D129 L130 S156 A157 G13 G15 K16 S17 A18 F28 V29 P30 E31 Y32 P34 T35 G60 N116 K117 D119 L120 S146 A147
BS02 MG A S27 T45 S17 T35
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:3pit, PDBe:3pit, PDBj:3pit
PDBsum3pit
PubMed
UniProtO08989|RASM_MOUSE Ras-related protein M-Ras (Gene Name=Mras)

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