Structure of PDB 3pii Chain A

Receptor sequence
>3piiA (length=337) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
MKAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWP
VKPKLPLIPGHEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLS
GQETLCEHQKNAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAG
VTTYKALKVTGAKPGEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEK
LELAKELGADLVVNPLKEDAAKFMKEKVGGVHAAVVTAVSKPAFQSAYNS
IRRGGACVLVGLPPEEMPIPIFDTVLNGIKIIGSIVGTRKDLQEALQFAA
EGKVKTIIEVQPLEKINEVFDRMLKGQINGRVVLTLE
3D structure
PDB3pii Crystal Structure of mutant of ht- Alcohol dehydrogenase
ChainA
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C38 H39 T40 H43 H61 E62 C92 C95 C98 C106 K110 C148 T152 R331
Catalytic site (residue number reindexed from 1) C38 H39 T40 H43 H61 E62 C92 C95 C98 C106 K110 C148 T152 R331
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C38 H61 E62 C148 C38 H61 E62 C148
BS02 ZN A C92 C95 C98 C106 C92 C95 C98 C106
BS03 BMD A T40 H61 W87 C148 T40 H61 W87 C148
Gene Ontology
Molecular Function
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3pii, PDBe:3pii, PDBj:3pii
PDBsum3pii
PubMed
UniProtP42328|ADH3_GEOSE Alcohol dehydrogenase

[Back to BioLiP]