Structure of PDB 3phd Chain A

Receptor sequence
>3phdA (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
PLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYIN
GHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFG
ED
3D structure
PDB3phd Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.-
3.5.1.98: histone deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W35 G46 R47 Y48 W74 Y76 Y81 W35 G46 R47 Y48 W74 Y76 Y81
BS02 ZN A C37 C40 H56 H62 C37 C40 H56 H62
BS03 ZN A C25 C28 C45 H52 C25 C28 C45 H52
BS04 ZN A C5 H7 C75 C78 C5 H7 C75 C78
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:3phd, PDBe:3phd, PDBj:3phd
PDBsum3phd
PubMed22069321
UniProtQ9UBN7|HDAC6_HUMAN Histone deacetylase 6 (Gene Name=HDAC6)

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