Structure of PDB 3ph7 Chain A

Receptor sequence
>3ph7A (length=347) Species: 5855 (Plasmodium vivax) [Search protein sequence]
AFFRNMYDKYRDAFLSHLNEYSLEEEIKEHISKYYKLLFDYNCLGGKNNR
GILVILIYEYVKNRDINSSEWEKAACLAWCIEILQAAFLVADDIMDKGEM
RRNKYCWYLLKDVETKNAVNDVLLLYNSIYKLIEIYLRNESCYVDVIATF
RDATLKTIIGQHLDTNIFSDKYSDEIDVNNINVPEQPVIDINMINFGVYK
NIVIHKTAYYSFFLPIVCGMLLAGIAVDNLIYKKIEDISMLMGEYFQIHD
DYLDIFSDIQNNKLTWPLIKTFELCSEPDKIKIVKNYGKNNLACVKVIDS
LYEQYKIRKHYESYEKAQKAKILSAINELHHEGIEYVLKYLLEILFT
3D structure
PDB3ph7 Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K81 A121 D126 D130 R135 D198 K243 F283 D287 D288
Catalytic site (residue number reindexed from 1) K47 A87 D92 D96 R101 D164 K206 F246 D250 D251
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GRG A G80 K81 R84 Q119 F122 L123 R135 R136 I192 Q195 Y247 F283 G46 K47 R50 Q85 F88 L89 R101 R102 I158 Q161 Y210 F246
Gene Ontology
Molecular Function
GO:0004161 dimethylallyltranstransferase activity
GO:0004337 geranyltranstransferase activity
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0045337 farnesyl diphosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ph7, PDBe:3ph7, PDBj:3ph7
PDBsum3ph7
PubMed21084289
UniProtA5K4U6

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