Structure of PDB 3pdo Chain A

Receptor sequence
>3pdoA (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
MIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFG
RFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVEL
REPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFH
YLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPS
3D structure
PDB3pdo Bidirectional binding of invariant chain peptides to an MHC class II molecule.
ChainA
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q9 R50 F51 A52 S53 F54 G58 N62 N69 M73 Q10 R51 F52 A53 S54 F55 G59 N63 N70 M74
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3pdo, PDBe:3pdo, PDBj:3pdo
PDBsum3pdo
PubMed21115828
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

[Back to BioLiP]