Structure of PDB 3pd9 Chain A

Receptor sequence
>3pd9A (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGEC
3D structure
PDB3pd9 Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HA5 A Y58 P86 L87 T88 R93 G138 S139 T140 E190 M193 Y58 P86 L87 T88 R93 G138 S139 T140 E190 M193 MOAD: Ki=494nM
PDBbind-CN: -logKd/Ki=6.22,Ki=600nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3pd9, PDBe:3pd9, PDBj:3pd9
PDBsum3pd9
PubMed21067182
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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