Structure of PDB 3pd3 Chain A

Receptor sequence
>3pd3A (length=145) Species: 29292 (Pyrococcus abyssi) [Search protein sequence]
MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDE
KNPEEVSLKAIEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNR
VYQGLKERGFNVGKAPFGYYKAFKISCKGHPLAELSRTIVPEEAR
3D structure
PDB3pd3 Mechanistic insights into cognate substrate discrimination during proofreading in translation
ChainA
Resolution1.86 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.1.1.3: threonine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3T A A19 V45 P80 F81 A82 A94 F117 G118 Y119 Y120 K121 A19 V45 P80 F81 A82 A94 F117 G118 Y119 Y120 K121 MOAD: Kd=36.2uM
PDBbind-CN: -logKd/Ki=4.44,Kd=36.2uM
Gene Ontology
Molecular Function
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3pd3, PDBe:3pd3, PDBj:3pd3
PDBsum3pd3
PubMed21098258
UniProtQ9UZ14|SYT_PYRAB Threonine--tRNA ligase (Gene Name=thrS)

[Back to BioLiP]