Structure of PDB 3p7y Chain A

Receptor sequence
>3p7yA (length=363) Species: 550 (Enterobacter cloacae) [Search protein sequence]
AEKLFTPLKVGAVTAPNRVFMAPLTRLRSIEPGDIPTPLMGEYYRQRASA
GLIISEATQISAQAKGYAGAPGLHSPEQIAAWKKITAGVHAEDGRIAVQL
WHTGRISHSSIQPGGQAPVSASALNANTRTSLRDENGNAIRVDTTTPRAL
ELDEIPGIVNDFRQAVANAREAGFDLVELHSAHGYLLHQFLSPSSNQRTD
QYGGSVENRARLVLEVVDAVCNEWSADRIGIRVSPIGTFQNVDNGPNEEA
DALYLIEELAKRGIAYLHMSETDLAGGKPYSEAFRQKVRERFHGVIIGAG
AYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNPQRPESFY
GGGAEGYTDYPSL
3D structure
PDB3p7y A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity.
ChainA
Resolution1.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T26 H181 H184 Y186 R233 Q241
Catalytic site (residue number reindexed from 1) T25 H180 H183 Y185 R232 Q240
Enzyme Commision number 1.6.99.1: NADPH dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A P24 L25 T26 A58 Q100 H181 H184 R233 L275 A302 F322 G323 R324 Y351 P23 L24 T25 A57 Q99 H180 H183 R232 L274 A301 F321 G322 R323 Y350
BS02 P7Y A T26 W102 H181 H184 Y186 L275 T25 W101 H180 H183 Y185 L274
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3p7y, PDBe:3p7y, PDBj:3p7y
PDBsum3p7y
PubMed21374779
UniProtP71278

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