Structure of PDB 3p72 Chain A

Receptor sequence
>3p72A (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
HPICEVSKVASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLAT
LMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLP
ALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKL
EKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFA
FLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDN
SDKFPVYKYPGKGCPLVPR
3D structure
PDB3p72 Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E128 Y130 K132 S154 W230 D235 V236 K237 E128 Y130 K132 S154 W230 D235 V236 K237
External links
PDB RCSB:3p72, PDBe:3p72, PDBj:3p72
PDBsum3p72
PubMed19726719
UniProtP07359|GP1BA_HUMAN Platelet glycoprotein Ib alpha chain (Gene Name=GP1BA)

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