Structure of PDB 3p4x Chain A

Receptor sequence
>3p4xA (length=399) Species: 2336 (Thermotoga maritima) [Search protein sequence]
EFWNEYEDFRSFFKKKFGKDLTGYQRLWAKRIVQGKSFTMVAPTGVGKTT
FGMMTALWLARKGKKSALVFPTVTLVKQTLERLQKLADEKVKIFGFYSSM
KKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDVDAV
LKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSA
TAKPRGIRPLLFRDLLNFTVGRLVSVARNITHVRISSRSKEKLVELLEIF
RDGILIFAQTEEEGKELYEYLKRFKFNVGETWSEFEKNFEDFKVGKINIL
IGVQAYDLPERIKYVIFWGTPSGPDVYTYIQASGRSSRILNGVLVKGVSV
IFEEDEEIFESLKTRLLLIAEEEIIEEAEANWKELVHEVEESRRRSERE
3D structure
PDB3p4x The Conformational Flexibility of the Helicase-like Domain from Thermotoga maritima Reverse Gyrase Is Restricted by the Topoisomerase Domain.
ChainA
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A F71 F75 D78 T80 Q83 G103 G105 K106 T107 T108 F13 F17 D20 T22 Q25 G45 G47 K48 T49 T50
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:3p4x, PDBe:3p4x, PDBj:3p4x
PDBsum3p4x
PubMed21627332
UniProtO51934|RGYR_THEMA Reverse gyrase (Gene Name=rgy)

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