Structure of PDB 3p34 Chain A

Receptor sequence
>3p34A (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSPEFDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVS
KWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESY
LTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLR
TWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTY
RLSLLEEYGCCKELASRLRYARTMVDKLLS
3D structure
PDB3p34 From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W414 D416 Y485 H489 L490 L491 R516 F535 H538 K540 W52 D54 Y123 H127 L128 L129 R154 F173 H176 K178
External links
PDB RCSB:3p34, PDBe:3p34, PDBj:3p34
PDBsum3p34
PubMed21472932
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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