Structure of PDB 3p2z Chain A

Receptor sequence
>3p2zA (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEFDCHLSDMLQQLHSVEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDN
SVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLK
YFRNYMSEHLLKAGANITPDELARLPYLRTWFRTRSAIILHLSNGSVQIN
FFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYA
RTMVDKLLSS
3D structure
PDB3p2z From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
ChainA
Resolution1.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W414 V415 D416 H489 L490 L491 R516 F535 H538 K540 W34 V35 D36 H109 L110 L111 R133 F152 H155 K157
External links
PDB RCSB:3p2z, PDBe:3p2z, PDBj:3p2z
PDBsum3p2z
PubMed21472932
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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