Structure of PDB 3p27 Chain A

Receptor sequence
>3p27A (length=433) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLL
YDLNIVNQSQLRKLQRWIMDQTVTVSICTSHFSTHRANFTIVDAPGVPNA
IMGISQADMAILCVDCSTFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNV
DWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEV
RQWYNGPNLMSTLENAAFKISKENEGINKDDPFLFSVLEIIPSKLALVSG
KLESGSIQPGESLTIYPSEQSCIVDKIQVGSQQHEETDVAIKGDFVTLKL
RKAYPEDIQNGDLAASVDYSSIHSAQCFVLELTTFDMNRPLLPGTPFILF
IGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAFVEIELIEVKRWI
PLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ
3D structure
PDB3p27 Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
ChainA
Resolution2.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D177 K180 S181 T232
Catalytic site (residue number reindexed from 1) D39 K42 S43 T74
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A V176 D177 G179 K180 S181 T182 K314 D316 N317 S352 G353 F354 V38 D39 G41 K42 S43 T44 K146 D148 N149 S184 G185 F186
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3p27, PDBe:3p27, PDBj:3p27
PDBsum3p27
PubMed21102444
UniProtP32769|HBS1_YEAST Elongation factor 1 alpha-like protein (Gene Name=HBS1)

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