Structure of PDB 3p1g Chain A

Receptor sequence
>3p1gA (length=157) Species: 438045 (Xenotropic MuLV-related virus) [Search protein sequence]
AETHGTRPDLTDQPIPDADYTWYTDGSSFLQEGQRRAGAAVTTETEVIWA
RALPAGTSAQRAELIALTQALKMAEGKKLNVYTDSRYAFATAHVHSEGRE
IKNKNEILALLKALFLPKRLSIIHCPGHQKGNSAEARGNRMADQAAREAA
MKAVLET
3D structure
PDB3p1g Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D524 E562 D583 D25 E63 D84
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:3p1g, PDBe:3p1g, PDBj:3p1g
PDBsum3p1g
PubMed22252812
UniProtA1Z651|POL_XMRV6 Gag-Pol polyprotein (Gene Name=gag-pol)

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