Structure of PDB 3ozp Chain A

Receptor sequence
>3ozpA (length=572) Species: 93504 (Ostrinia furnacalis) [Search protein sequence]
EDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGE
ADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTP
KLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSF
FGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNY
YSIESIKRTIEAMAAVKLNTFHWHITDSQSFPFVTTKRPNLYKFGALSPQ
KVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPW
KSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEA
CWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLI
LWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYD
ALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAA
LWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERLVR
MGIQAESLQPEWCYQNEGYCYS
3D structure
PDB3ozp Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D367 E368
Catalytic site (residue number reindexed from 1) D345 E346
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OAN A R220 D367 E368 W424 W448 Y475 D477 W490 W524 E526 R198 D345 E346 W402 W426 Y453 D455 W468 W502 E504 MOAD: Ki=0.24uM
PDBbind-CN: -logKd/Ki=6.62,Ki=0.24uM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016231 beta-N-acetylglucosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0006517 protein deglycosylation
GO:0006689 ganglioside catabolic process
GO:0030203 glycosaminoglycan metabolic process
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ozp, PDBe:3ozp, PDBj:3ozp
PDBsum3ozp
PubMed21692744
UniProtQ06GJ0|HEXC_OSTFU Chitooligosaccharidolytic beta-N-acetylglucosaminidase

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