Structure of PDB 3oz2 Chain A

Receptor sequence
>3oz2A (length=397) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
GMETYDVLVVGGGPGGSTAARYAAKYGLKTLMIEKRPEIGSPVRCGEGLS
KGILNEADIKADRSFIANEVKGARIYGPSEKRPIILQSEKAGNEVGYVLE
RDKFDKHLAALAAKAGADVWVKSPALGVIKENGKVAGAKIRHNNEIVDVR
AKMVIAADGFESEFGRWAGLKSVILARNDIISALQYRMINVDVDPDYTDF
YLGSIAPAGYIWVFPKGEGMANVGIGSSINWIHNRFELKNYLDRFIENHP
GLKKGQDIQLVTGGVSVSKVKMPITMPGLMLVGDAARLIDPITGGGIANA
IVSGMYAAQVTKEAIESNDYSPQMMQKYEKLIKERFERKHLRNWVAKEKL
AMLSDDTLDKLVDIVSEQVLTTISVEAILKAIAEKYPEVVKELEDLI
3D structure
PDB3oz2 Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.101: 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H].
Interaction with ligand
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0045550 geranylgeranyl reductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0046467 membrane lipid biosynthetic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3oz2, PDBe:3oz2, PDBj:3oz2
PDBsum3oz2
PubMed20869368
UniProtQ9HKS9|GGR_THEAC Digeranylgeranylglycerophospholipid reductase (Gene Name=Ta0516)

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