Structure of PDB 3osu Chain A

Receptor sequence
>3osuA (length=246) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIK
AKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMR
MKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPG
QANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELK
EQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
3D structure
PDB3osu Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G15 S141 Q151 Y154 K158
Catalytic site (residue number reindexed from 1) G15 S141 Q151 Y154 K158
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N89 K158 N89 K158
Gene Ontology
Molecular Function
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0051287 NAD binding
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3osu, PDBe:3osu, PDBj:3osu
PDBsum3osu
PubMed
UniProtP0A0H9|FABG_STAAM 3-oxoacyl-[acyl-carrier-protein] reductase FabG (Gene Name=fabG)

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