Structure of PDB 3osa Chain A

Receptor sequence
>3osaA (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCNVVPSYDLLLEMLDA
3D structure
PDB3osa Coupling of receptor conformation and ligand orientation determine graded activity.
ChainA
Resolution2.296 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KN3 A E353 L387 M421 I424 G521 E48 L82 M115 I118 G215
External links
PDB RCSB:3osa, PDBe:3osa, PDBj:3osa
PDBsum3osa
PubMed20924370
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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