Structure of PDB 3of1 Chain A

Receptor sequence

>3of1A (length=246) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDY
FYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAATVVATSDCLL
WALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDT
KIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVA
LLNDLPRQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLNDPTRH

3D structure

PDB

3of1 Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling.

Chain

Resolution

2.21 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CMP	A	I212 F231 V233 F247 G248 E249 L250 A251 R258 A259 A260 Y309	I42 F61 V63 F77 G78 E79 L80 A81 R88 A89 A90 Y139
BS02	CMP	A	I330 I357 N358 F366 G367 E368 V369 A370 R377 Q378 P413	I160 I187 N188 F196 G197 E198 V199 A200 R207 Q208 P243

External links

PDB	RCSB:3of1, PDBe:3of1, PDBj:3of1
PDBsum	3of1
PubMed	21070946
UniProt	P07278\|KAPR_YEAST cAMP-dependent protein kinase regulatory subunit (Gene Name=BCY1)

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