Structure of PDB 3obb Chain A

Receptor sequence
>3obbA (length=295) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARS
ARDAVQGADVVISMLPASQHVEGLYLDDDGLLAHIAPTLVLECSTIAPTS
ARKIHAAARERGLAMLDAPVSGGTAGAAAGTLTFMVGGDAEALEKARPLF
EAMGRNIFHAGPDGAGQVAKVCNNQLLAVLMIGTAEAMALGVANGLEAKV
LAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQLMAKDLGLA
QEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLFDPTQ
3D structure
PDB3obb Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine Dehydrogenase.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.387: L-serine 3-dehydrogenase (NAD(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPE A G123 G124 K171 N175 W214 Y219 F239 G122 G123 K170 N174 W213 Y218 F238
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0006565 L-serine catabolic process
GO:0009083 branched-chain amino acid catabolic process
GO:0016054 organic acid catabolic process
GO:0051289 protein homotetramerization

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Molecular Function
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Biological Process
External links
PDB RCSB:3obb, PDBe:3obb, PDBj:3obb
PDBsum3obb
PubMed22128181
UniProtQ9I5I6|SERDH_PSEAE NAD-dependent L-serine dehydrogenase (Gene Name=PA0743)

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