Structure of PDB 3o7b Chain A

Receptor sequence
>3o7bA (length=216) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
MGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAM
KSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRL
PRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREK
GGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSL
YVTSRVLCEYERVRAH
3D structure
PDB3o7b Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
ChainA
Resolution1.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR A R153 S191 L192 G193 R153 S191 L192 G193
BS02 SAH A F147 R148 E149 G169 F171 G174 S191 L192 Y197 V202 F147 R148 E149 G169 F171 G174 S191 L192 Y197 V202
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0019843 rRNA binding
GO:0070037 rRNA (pseudouridine) methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0042254 ribosome biogenesis
GO:0070475 rRNA base methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3o7b, PDBe:3o7b, PDBj:3o7b
PDBsum3o7b
PubMed21087996
UniProtO29524|NEP1_ARCFU Ribosomal RNA small subunit methyltransferase Nep1 (Gene Name=nep1)

[Back to BioLiP]