Structure of PDB 3o4n Chain A

Receptor sequence
>3o4nA (length=133) Species: 11886 (Rous sarcoma virus) [Search protein sequence]
QIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAAQHHWATA
IAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTQAMVERANRLLKDK
IRVLAEGDGFMKRIPASKQGELLAKAMYALNHF
3D structure
PDB3o4n A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A D64 D121 D6 D63
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3o4n, PDBe:3o4n, PDBj:3o4n
PDBsum3o4n
PubMed21857987
UniProtO92956|POL_RSVSB Gag-Pol polyprotein (Gene Name=gag-pol)

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