Structure of PDB 3o37 Chain A

Receptor sequence
>3o37A (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLS
KPEVEYDCEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLT
VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNE
PDSEVANAGIKLENYFEELLKNLYP
3D structure
PDB3o37 TRIM24 links a non-canonical histone signature to breast cancer.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N825 E826 D827 W828 Q833 N834 G835 G836 E837 L838 C840 C841 E842 F860 P861 G863 N1 E2 D3 W4 Q9 N10 G11 G12 E13 L14 C16 C17 E18 F36 P37 G39
BS02 ZN A C841 C844 C870 C17 C20 C46
BS03 ZN A C829 C832 H849 C852 C5 C8 H25 C28
External links
PDB RCSB:3o37, PDBe:3o37, PDBj:3o37
PDBsum3o37
PubMed21164480
UniProtO15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)

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