Structure of PDB 3o36 Chain A

Receptor sequence
>3o36A (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
SPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRD
LSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSL
AFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLI
FQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP
3D structure
PDB3o36 TRIM24 links a non-canonical histone signature to breast cancer.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V928 F979 N980 E981 V106 F157 N158 E159
BS02 ZN A C829 C832 H849 C852 C7 C10 H27 C30
BS03 ZN A C841 C844 C867 C870 C19 C22 C45 C48
External links
PDB RCSB:3o36, PDBe:3o36, PDBj:3o36
PDBsum3o36
PubMed21164480
UniProtO15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)

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