Structure of PDB 3o34 Chain A

Receptor sequence
>3o34A (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSK
PEVEYDCDAPSHKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVP
LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEF
NEPDSEVANAGIKLENYFEELLKNLYP
3D structure
PDB3o34 TRIM24 links a non-canonical histone signature to breast cancer.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F924 V928 E978 F979 N980 E981 F95 V99 E149 F150 N151 E152
BS02 ZN A C829 C832 H849 C852 C4 C7 H24 C27
BS03 ZN A C841 C844 C867 C870 C16 C19 C42 C45
External links
PDB RCSB:3o34, PDBe:3o34, PDBj:3o34
PDBsum3o34
PubMed21164480
UniProtO15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)

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