Structure of PDB 3o2f Chain A

Receptor sequence
>3o2fA (length=228) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLI
SLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAK
SGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNND
TQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLV
KKYSQFINFPIYVWSSKTKTVWDWELMN
3D structure
PDB3o2f Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P54 A A111 K114 M154 F195 F199 I247 A43 K46 M86 F127 F131 I179
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:3o2f, PDBe:3o2f, PDBj:3o2f
PDBsum3o2f
PubMed23995768
UniProtP41148|ENPL_CANLF Endoplasmin (Gene Name=HSP90B1)

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