Structure of PDB 3o1x Chain A

Receptor sequence
>3o1xA (length=115) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
RPGGDTIFGKIIRKEIPAKIIFEDDQCLAFHDISPQAPTHFLVIPKKHIS
QISAAEDADESLLGHLMIVGKKAAADLGLKKGYRMVVNEGSDGGQSVYHV
HLHVLGGRQMNWPPG
3D structure
PDB3o1x Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
ChainA
Resolution1.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.-
3.9.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADN A F41 D43 I44 S45 H112 H114 F30 D32 I33 S34 H101 H103
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0008234 cysteine-type peptidase activity
GO:0016787 hydrolase activity
GO:0016929 deSUMOylase activity
GO:0043530 adenosine 5'-monophosphoramidase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0009154 purine ribonucleotide catabolic process
GO:0016926 protein desumoylation
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3o1x, PDBe:3o1x, PDBj:3o1x
PDBsum3o1x
PubMed20940308
UniProtP80912|HINT1_RABIT Adenosine 5'-monophosphoramidase HINT1 (Gene Name=HINT1)

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